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近年来许多实验室发展了一种新的实验模型,从成年哺乳动物,大鼠,兔,狗等心室分离出能自发跳动的单个细胞。这样的模型用来研究细胞的生化调节机制和对药物的反应特别适宜,它与组织匀浆相比保持较完整的细胞结构,与组织薄片相比具有较纯的细胞群,不受神经和激素的影响。而从成年动物心室所分得细胞之间较培养的胚胎细胞之间具有更大的相似性,更适宜于生化、药理等的研究。因此受到
In recent years, many laboratories have developed a new experimental model to separate spontaneous beating single cells from adult mammalian, rat, rabbit, dog and other ventricles. Such models are particularly suitable for studying the biochemical regulatory mechanisms of cells and their response to drugs. They maintain a more intact cellular structure compared to tissue homogenates and have a purer cell population compared to tissue slices, independent of neurological and hormonal Impact. The cells isolated from the adult animal ventricle have more similarities between cultured embryonic cells and are more suitable for biochemical and pharmacological studies. So by