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目的观察比较甘精胰岛素加短效胰岛素和胰岛素泵短期强化治疗对2型糖尿病的临床疗效。方法选取2012年6月~2013年6月期间本院收治的40例2型糖尿病患者,随机分为两组。观察组20例,应用甘精胰岛素加短效胰岛素进行治疗;对照组20例,应用胰岛素泵短期强化治疗。观察比较两组的治疗效果。结果在连续治疗3个月后,观察组和对照组在治疗后空腹时血糖水平、餐后两小时血糖水平上均有明显下降,但是两组之间比较,差异无统计学意义(P>0.05)。此外,观察组的胰岛素用量和治疗费用均低于对照组(P<0.05),低血糖的发生次数则比对照组多(P<0.05)。结论甘精胰岛素加短效胰岛素和胰岛素泵短期强化治疗2型糖尿病的效果相当,前者价格相对便宜,而后者并发低血糖的几率较低,医生应针对患者具体情况合理选择给药方式。
Objective To compare the clinical effects of insulin glargine plus short-acting insulin and insulin pump short-term intensive treatment on type 2 diabetes mellitus. Methods Forty patients with type 2 diabetes admitted to our hospital from June 2012 to June 2013 were randomly divided into two groups. 20 cases in the observation group were treated with insulin glargine and short-acting insulin; 20 cases in the control group were treated with short-term intensive insulin pump. Observed and compared the treatment effect of two groups. Results After 3 months of continuous treatment, the fasting blood glucose level and the two-hour postprandial blood glucose level of the observation group and the control group both decreased significantly after treatment, but there was no significant difference between the two groups (P> 0.05 ). In addition, the amount of insulin and the cost of treatment in the observation group were lower than those in the control group (P <0.05), and the incidence of hypoglycemia was more than that in the control group (P <0.05). Conclusion Glargard insulin plus short-acting insulin and insulin pump short-term intensive treatment of type 2 diabetes, the effect is relatively, the former is relatively cheap, while the latter with low risk of hypoglycemia, the doctor should be based on the specific circumstances of patients with a reasonable choice of mode of administration.