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[目的]应用组织多普勒成像(DTI)技术评价不同程度冠心病患者的心脏舒张功能,并探讨其临床意义.[方法]对30例健康对照者及40例患有不同程度冠状动脉狭窄的患者分别行常规多普勒及DTI检查,根据冠状动脉狭窄的程度分为异常A组(22例狭窄率超过50%)和异常B组(18例狭窄率不足50%).应用常规多普勒技术主要测量二尖瓣口早期充盈速度E峰(E)和舒张晚期充盈速度A峰(A)及E/A比值;DTI检查主要测量左心室等容舒张时间(IVRT)、二尖瓣环舒张早期运动速度(Ve)、舒张晚期运动速度(Va)和Ve/Va比值,并对所得数据进行对比研究.[结果]异常组Ve,Ve/Va较对照组明显降低(P<0.05),异常组IVRT较对照组明显延长(P<0.05);异常A组IVRT较异常B组明显延长(P<0.05);异常B组Ve,Ve/Va较对照组显著降低(P<0.05);异常B组的IVRT较对照组显著延长(P<0.05).[结论]DTI技术是评价不同程度冠心病患者左心室舒张功能的可靠方法.
[Objective] To evaluate the clinical significance of diastolic function in patients with coronary heart disease by tissue Doppler imaging (DTI) technique. [Methods] Thirty healthy controls and 40 patients with varying degrees of coronary artery stenosis According to the degree of coronary artery stenosis, the patients were divided into group A (22 cases with stenosis more than 50%) and group B (18 cases with stenosis less than 50%) according to the degree of coronary artery stenosis.Using routine Doppler The technique mainly used to measure the ratio of E peak (E) and late diastolic filling velocity (A) and E / A of early filling velocity of mitral valve orifice; DTI examination mainly measured left ventricular isovolumic relaxation time (IVRT), mitral annular dilatation Ve, Va and Ve / Va ratios were compared between the two groups. [Results] The levels of Ve, Ve / Va in the abnormal group were significantly lower than those in the control group (P <0.05) (P <0.05); IVRT in abnormal group A was significantly longer than that in abnormal group B (P <0.05); Ve, Ve / Va in abnormal group B was significantly lower than that in control group (P <0.05) Group IVRT significantly longer than the control group (P <0.05). [Conclusion] The DTI technique is to evaluate the reliability of left ventricular diastolic function in patients with different degrees of coronary heart disease Law.