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乙型肝炎 e 抗原(HBeAg)的存在提示病毒复制活跃,并常伴发更严重肝疾患.HBeAg 消失和抗-HBe 出现是病毒复制由活跃转为不活跃的标志。本文选择无症状慢性乙型肝炎患者,其 HBsAg 阳性或转氨酶升高,并符合下列标准者46例作研究。标准为:①转氨酶两次升高,其间相隔6个月以上;②血清 HBsAg 及 HBeAg 阳性,肝细胞 HBcAg 阳性;③与肝炎有关的症状不足而求医者。对此46例随访1～4(平均2.24)年,其中男28例,女18例;年龄平均32.5(10～68)岁·分析其 HBeAg 清除情
The presence of hepatitis B e antigen (HBeAg) suggests that viral replication is active and is often accompanied by more severe liver disorders. The disappearance of HBeAg and the appearance of anti-HBe are hallmarks of viral replication from active to inactive. In this paper, asymptomatic patients with chronic hepatitis B, HBsAg-positive or elevated transaminases, and meet the following criteria in 46 cases for the study. Criteria: ① elevated transaminase twice, during which more than 6 months; ② serum HBsAg and HBeAg positive, positive HBcAg hepatocytes; ③ symptoms associated with hepatitis and seek medical treatment. 46 cases were followed up for 1-4 years (average 2.24) years, including 28 males and 18 females; the average age was 32.5 (range, 10-68 years). Analysis of HBeAg clearance