新生儿惊厥(Neonatal convulsion)是中枢神经系统功能紊乱的一个症状,常是某种原因引起大脑皮质突然大量异常放电,导致惊厥发生。新生儿惊厥发作常提示病情严重,病死率较高,易有后遗症,特别是大脑发育障碍,给社会及家庭带来不良影响,应引起重视。新生儿惊厥的发病率约占活产婴的1.2%。由于新生儿惊厥的症状不典型,难以辨认,所以易误诊。一、病理生理由于新生儿大脑皮层薄,皮质神经细胞的胞浆、胞质分化不全,其树突髓鞘、突触的形成尚不完善,神经胶质和神经细胞之间的正常联系尚未建立,所以皮层限局性异常放电不易兴奋邻近组织,容易局限于一个大脑半球之内,而不向对侧半球传 Neonatal convulsion is a symptom of central nervous system dysfunction. It is often caused by a sudden, abnormal discharge of a large number of abnormalities in the cerebral cortex, leading to convulsions. Newborns convulsions seizures often prompted a serious condition, high mortality, easy to have sequelae, especially brain development disorders, to bring adverse social and family, should pay attention. The incidence of neonatal convulsions accounted for about 1.2% of live births. As the symptoms of neonatal convulsions atypical, difficult to identify, so easy to misdiagnosis. First, the pathophysiology As neonatal cerebral cortex thin, cortical neuronal cytoplasm, cytoplasmic dysgenesis, the dendrite sheath, the formation of synapses is not perfect, the normal contact between glia and nerve cells has not been established , So the abnormal cortical discharge abnormal excitement is not easy to adjacent tissues, easily confined to a hemisphere within the brain, not to the contralateral hemisphere