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作者曾于1973,1978年报告将豚鼠暴露于频率为20千赫、声压级120分贝之噪声下1小时、3周后检查内耳损伤的结果。1979年又报告将暴露的时间加倍,而外毛细胞损伤的范围并不扩大,有几例反而缩小。是否由于动物在第一次暴露于强噪声后毛细胞发生疲劳因而保护毛细胞免受再次噪声的损害?作者对此现象作了进一步观察。此次研究除了重复以前的实验外,还将暴露噪声时间缩短,动物的存活时间延长。全部实验都是用生长5～6周、非纯种之白化豚鼠,每只动物的两耳,一侧暴露噪声,另一侧留作对照,噪声频率为20千赫,声压级为120分贝,暴露时间为30,15及7.5分钟,动物存活时间为3,6及12周。耳蜗采用铺片法处理,用相差显微镜观
The authors reported in 1973 and 1978 that guinea pigs were exposed to noise of 120 kHz at a sound pressure level of 120 kHz for 1 hour and 3 weeks later to examine the results of inner ear lesions. In 1979, it was reported that doubling the exposure time, while the range of external hair cell damage did not expand, but a few cases narrowed. Did the authors protect the hair cells from further noise as a result of animals’ fatigue after the first exposure to strong noise? The authors further examined this phenomenon. In addition to repeating the previous experiment, this study will also shorten the time of exposure to noise and prolong the survival time of animals. All experiments were performed with albino guinea pigs of non-purebred species grown for 5 to 6 weeks, with each animal having two ears exposed on one side with noise on the other side as control with a noise frequency of 20 kHz and a sound pressure level of 120 dB , Exposure times of 30, 15 and 7.5 minutes, and animal survival times of 3, 6 and 12 weeks. The cochlea treated with a piece of film, with a phase contrast microscope