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本文旨在研究可用于文物保护的低毒、温和的新型中草药复方抑菌剂。选择大青叶和穿心莲两味中草药。通过L9(34)正交设计方法优化其提取工艺,并按中草药配伍规则配置成复方,通过对3种常见病原菌——金黄色葡萄球菌、枯草芽孢杆菌和大肠杆菌的抑菌试验来说明其抑菌活性。大青叶和穿心莲提取液复方制剂对于3种常见病原菌均表现出明显的抑菌活性,效果优于单味大青叶和穿心莲提取物。
The purpose of this paper is to study a new type of Chinese herbal compound antibacterial agent with low toxicity and mild temperature that can be used for cultural relic protection. Choose Folium and Andrographis two herbs. The extraction process was optimized by the L9 (34) orthogonal design method, and the compound prescription was formulated according to the compatibility rules of Chinese herbal medicine. The antibacterial tests of three kinds of common pathogens, Staphylococcus aureus, Bacillus subtilis and Escherichia coli, Bacteria activity. Folium extract and Andrographis paniculata extracts of the three common pathogenic bacteria showed significant antibacterial activity, the effect is better than single Folium Andrographis extract.