Since the multifocal field-change concept andthe implantation of tumor cells probably contributeto the high incidence of postoperative recurrence ornew occurrences of bladder tumors, it seems futileto rely solely on TUR or tumor resection and ful-guration for treatment. Antineoplastic agent as Thio- Since the multifocal field-change concept and the implantation of tumor cells probably contribute to the high incidence of postoperative recurrence or new occurrences of bladder tumors, it seems futileto rely solely on TUR or tumor resection and ful-guration for treatment. Antineoplastic agent as Thio-