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目的 分析院前急救治疗重型颅脑外伤患者的临床疗效。方法 以合作医院2019年1月至2020年12月收治的60例重型颅脑外伤患者为本次研究对象，所选患者以入院方式差异分为常规组和观察组，各30例，其中常规组患者为自行到院就诊，入院前未采取急救措施，而观察组患者则由急救中心送入医院，入院前采取院前急救。统计对比两组患者的治疗效果、病死率、预后效果。结果 观察组患者的治疗有效率显著高于常规组（P＜0.05），而2周内病死率显著低于常规组（P＜0.05）；治疗后观察组患者的PT、APTT水平均显著低于常规组（P＜“,”Objective To analyze the clinical effect of pre hospital emergency treatment on patients with severe craniocerebral trauma. Methods The 60 patients with severe traumatic brain injury admitted to the cooperative hospital from January 2019 to December 2020 are the subjects of this study. The selected patients are divided into the conventional group and the observation group according to the difference in admission method， with 30 cases in each group， of which patients in the routine group In order to go to the hospital on their own， no emergency measures were taken before admission， while patients in the observation group were sent to the hospital by an emergency center， and pre-hospital first aid was taken before admission. The treatment effect， mortality， and prognosis effect of the two groups of patients were statistically compared. Results The effective rate of treatment in the observation group was significantly higher than that of the conventional group (P ＜0.05)， and the mortality within 2 weeks was significantly lower than that of the conventional group (P ＜0.05)， and the coagulation indexes such as PT and APTT of the observation group were significantly lower than the conventional group after treatment (P ＜0.05)， while PLT was significantly higher than the conventional group (P ＜0.05). One month after discharge， the MMSE score， Barthel score and QOL score of the observation group were significantly higher than those of the conventional group (P ＜0.05). Conclusion Paying attention to pre hospital first aid for patients with severe craniocerebral trauma can effectively improve the treatment effect， reduce the short-term mortality， improve the prognosis and improve the quality of life.