采用焦虑自评量表(SAS)和抑郁自评量表(SDS)对248例功能性消化不良(FD)患者进行心理测评及症状评分。随机将心理测评异常者分为治疗组及对照组,分别给予常规治疗及加用抗抑郁药文拉法新治疗;将治疗组有效的病例随机分成维持组及停药组,维持组继续给予文拉法新维持量治疗。比较治疗组及对照组的总有效率;观察半年中维持组及停药组的复发率。结果表明:文拉法新可提高FD患者常规治疗的有效率,半年维持治疗能有效降低复发率。 248 patients with functional dyspepsia (FD) were evaluated by psychology and symptom scores using self-rating anxiety scale (SAS) and depression self-rating scale (SDS). Patients with abnormal psychometric abnormalities were randomly divided into treatment group and control group, which were given routine treatment and anti-depressant drug Rafah new treatment respectively. The effective cases of treatment group were randomly divided into maintenance group and withdrawal group, and maintenance group continued to give Rafah new volume treatment. The total effective rate of the treatment group and the control group was compared. The recurrence rate of the maintenance and withdrawal groups in the six months were observed. The results showed that venlafaxine can improve the efficiency of routine treatment of FD patients, six months of maintenance treatment can effectively reduce the recurrence rate.