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目的探讨肾上腺结核继发Addison’s病的临床特点。方法回顾性分析36例肾上腺结核继发Addison’s病的临床资料,归纳总结并比较各临床表现发生情况,以发生率表示。结果36例肾上腺结核继发Addison’s病病例中32例(88.9%)伴有肾上腺外结核;33例行CT检查,随着病程的延长肾上腺由增大逐渐萎缩且钙化范围逐渐增大;综合临床,影像学表现和痰菌等判断,23例(63.9%)为活动性结核。结论肾上腺结核是我国Addison’s病的常见原因,且常伴有肾上腺外结核;肾上腺结核的CT特征与病程长短有关;如有活动性结核者,在用激素替代治疗的同时,应积极给予抗结核治疗。
Objective To investigate the clinical features of Addison’s disease secondary to adrenal tuberculosis. Methods Retrospective analysis of 36 cases of adrenal tuberculosis secondary to Addison’s disease clinical data, summarized and compared the occurrence of clinical manifestations, the incidence rate. Results Thirty-two cases of Addison’s disease secondary to adrenal tuberculosis were found in 36 cases (88.9%) with extra-adrenal tuberculosis. Thirty-three cases underwent CT examination. The adrenal gland gradually atrophied with the increase of the course of the disease and the range of calcification gradually increased. Imaging findings and sputum bacteria and other judgments, 23 cases (63.9%) were active tuberculosis. Conclusion Adrenal tuberculosis is a common cause of Addison’s disease in our country, and often accompanied by extra-adrenal tuberculosis; CT features of adrenal tuberculosis and duration of the disease; if active tuberculosis, hormone replacement therapy should be given at the same time, should be actively given anti-TB treatment .