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目的探讨以感觉神经病为主要表现的干燥综合征患者的临床特点。方法分析1例以感觉神经病为主要表现的干燥综合征患者的临床表现及电生理特点,结合国外文献复习予以分析总结。结果感觉神经病的诊断在临床上可早于干燥综合征,以不对称感觉异常起病,逐渐发展,深感觉障碍较为突出,可出现假性手足徐动。典型的电生理改变为广泛的感觉神经动作电位波幅降低,但不伴有神经传导速度减慢。结论感觉神经病是临床上较为少见的一类疾病,干燥综合征是其常见病因之一。
Objective To investigate the clinical features of patients with Sjögren’s syndrome, the main manifestation of which is sensory neuropathy. Methods One case of Sjogren ’s syndrome with sensory neuropathy as the main manifestation and its electrophysiological characteristics were analyzed and analyzed with the review of foreign literature. Results The diagnosis of sensory neuropathy may be earlier than that of Sjogren ’s syndrome in clinical practice. With the onset of asymmetric sensory abnormalities, the progressive development of deep sensory neuropathy may lead to the development of profound sensory disturbances. The typical electrophysiological changes to a wide range of sensory nerve action potential amplitude decreases, but not accompanied by slowing of nerve conduction velocity. Conclusion Sensory neuropathy is a relatively rare clinical disease, Sjogren’s syndrome is one of the common causes.