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目的探讨非缺血性心脏病(NIHD)患者窦性心律震荡(HRT)的变化及意义。方法选择161例NIHD患者及76例正常对照。前者按照随访中有无心血管事件发生分为事件组(101例)和无事件组(60例),均行24 h动态心电图、超声心动图等检查,记录临床资料,计算HRT的震荡初始(TO)和震荡斜率(TS)。结果 NIHD患者TO较对照组升高,TS较对照组降低(P<0.01)。与无事件组比较,事件组TO升高,TS降低(P<0.01)。TO与TS两项均异常是NIHD患者发生主要心血管事件强有力的预测因素。结论 HRT充分反映心脏自主神经功能,是NIHD患者病情评估或危险分层的有用指标。
Objective To investigate the changes and significance of sinus rhythm shock (HRT) in patients with nonischemic heart disease (NIHD). Methods 161 cases of NIHD patients and 76 normal controls were selected. The former was divided into event group (101 cases) and no incident group (60 cases) according to the presence or absence of cardiovascular events at follow-up. All patients underwent 24-hour Holter monitoring and echocardiography. The clinical data were recorded and the initial HRT ) And the oscillation slope (TS). Results TOHD in NIHD patients was higher than that in control group, TS was lower than that in control group (P <0.01). Compared with the non-event group, event group TO increased, TS decreased (P <0.01). Both TO and TS abnormalities are powerful predictors of major cardiovascular events in NIHD patients. Conclusion HRT fully reflects the function of cardiac autonomic nervous system, which is a useful indicator of disease status or risk stratification in patients with NIHD.