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【目的】探讨经皮冠状动脉介入术(PCI)支架植入前球囊预扩张对围手术期冠脉微循环功能损伤的影响。【方法】选择本院收治的40例稳定性心绞痛并拟行择期 PCI 的患者(加拿大心脏病学会的劳力型心绞痛分级<Ⅳ级),随机分为支架植入前无球囊预扩张组(未预扩张组,n =20)和支架植入行前球囊预扩张组(预扩张组,n =20)。PCI 术后,以压力导丝检测两组入选患者的冠状动脉微循环阻力指数(IMR),对比两组 PCI 术后 IMR 差异。【结果】非预扩张组 PCI 术后 IMR 值显著低于预扩张组,差异具有统计学意义(P <0.001)；PCI 术后,IMR≥22非预扩张组患者所占比例显著低于预扩张组患者(P <0.05)。【结论】PCI 术中,不行球囊预扩张而植入支架可减少 PCI术围手术期冠脉微循环功能损伤。“,”Objective]To investigate the effect of percutaneous coronary intervention (PCI)on the function of coro-nary microcirculation in patients with coronary microcirculation during perioperative period.[Method]Forty patients with stable angina (Canadian Cardiovascular Society class IV)in our hospital were selected and admitted for elective percutane-ous coronary intervention (PCI),They were randomized to the non pre-dilation group(n =20)and the pre-dilation group (n =20).After PCI,the index of microcirculatory resistance(IMR)of the two groups was detected by sensor-tipped guide wire,and the difference of IMR between the two groups after surguery was compared with .[Result]After PCI , IMR value of the non pre-dilation group was significantly lower than that in the pre-dilation group,the difference had sta-tistical significance (P <0.001);after PCI,IMR was more than or equal to 22,the proportion of the non pre-dilation group was significantly lower than that of the pre-dilation group (P <0.05).[Conclusions]In PCI operation,it can re-duce the damage of the coronary microcirculation in the perioperative period by the implantation of the stent without pre-dilation.