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慢性阻塞性肺疾病(COPD)和支气管哮喘是呼吸道最常见的两大疾患,二者的发病率在近年呈上升趋势,大量的研究表明,COPD与哮喘患者血清中的细胞因子IL-4、IL-8、IL-10均参与了二者的气道炎症反应,糖皮质激素对COPD和哮喘患者血清中IL-4、IL-8、IL-10是有影响的,本文就给予糖皮质激素治疗后,COPD和哮喘患者血清中IL-4、IL-8、IL-10的变化在国内外研究进展作一简要综述。
Chronic Obstructive Pulmonary Disease (COPD) and bronchial asthma are the two most common respiratory diseases, the incidence of which is on the rise in recent years. A large number of studies have shown that serum levels of cytokines IL-4, IL -8, IL-10 are involved in the airway inflammatory response of both, glucocorticoid on COPD and asthma serum IL-4, IL-8, IL-10 is affected, this article given glucocorticoid therapy After the changes of IL-4, IL-8 and IL-10 in the sera of patients with COPD and asthma, we briefly reviewed the research progress at home and abroad.