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目的原发性高血压目前被认为是胰岛素抵抗综合征的一部分,我们对老年高血压患者中有关因素进行分析讨论。方法高血压组68人,平均年龄65.7岁,对照组53例,平均年龄63.9岁。测空腹血糖(FBG)、胰岛素(FINS)、血脂4项甘油三酯(TG)。计算体重指数BM I=体重(kg)/身高(m)2、脂肪分布指数WHR=腰围/臀围、胰岛素敏感指数ISI=I/FBG×FINS。结果高血压组的BM I,WHR,FBG,FINS,TG水平高于对照组,ISI低于对照组。经多元分析,ISI与TG,BM I,WHR呈负相关,与HDL呈正相关。结论老年高血压组存在有胰岛素抵抗,这是造成高血压病并发冠心病发生的重要原因之一。
Objectives Essential hypertension is currently considered part of the syndrome of insulin resistance, and we discuss the relevant factors in elderly hypertensive patients. Methods Hypertension group 68 people, the average age of 65.7 years, control group of 53 patients, average age 63.9 years old. Fasting blood glucose (FBG), insulin (FINS), blood lipid four triglycerides (TG). Body mass index (kg) / height (m) 2. Fat distribution index WHR = waist circumference / hip circumference, insulin sensitivity index ISI = I / FBG × FINS. Results The levels of BM I, WHR, FBG, FINS and TG in hypertension group were higher than those in control group, and ISI was lower than that in control group. After multivariate analysis, ISI was negatively correlated with TG, BM I and WHR, and positively correlated with HDL. Conclusion There is insulin resistance in the elderly hypertensive group, which is one of the important causes of hypertension complicated with coronary heart disease.