目的 :探讨低氧反应和屏气反应在急性高原反应预测中的作用。方法 :在平原观察 113名入藏人员吸入 10 %低氧气体 10min和屏气过程中的血氧饱和度、心率和血压变化 ;进入高原后进行急性高原反应 (AMS)症状评分 ;两组数据进行相关分析 ,并对急性高原反应者和基本无反应者数据进行分析。结果 :吸入 10 %低氧气体过程中 ,动脉血氧饱和度进行性下降 ,心率迅速升高 ,血压普遍呈现先升高后降低的变化趋势。急性高原反应者吸入低氧气体 1min时的心率明显慢于基本无反应者。所观测指标均存在着较大的个体差异 ,但相关分析表明 ,AMS评分仅与吸入低氧气体 7min时的心率呈显著负相关 ,相关系数r为 - 0 .176。结论 :在平原单纯用低氧和屏气反应来预测36 5 8m高原地区的AMS发病情况意义可能有限。 Objective: To investigate the role of hypoxia and breath-hold reaction in predicting acute altitude sickness. Methods: The blood pressure, oxygen saturation, heart rate and blood pressure during the inhalation of 10% hypoxia for 10 minutes and breath holding were observed in 113 plains. Acute high altitude (AMS) symptom scores were obtained after entering the plateau. The data of two groups were correlated Analysis, and analysis of acute high altitude responders and non-responders data. Results: During the inhalation of 10% hypoxia, arterial oxygen saturation decreased progressively, heart rate increased rapidly, and blood pressure tended to increase firstly and then decrease. Acute altitude sickness inhaled hypoxia 1min heart rate was significantly slower than the basic non-responders. However, the correlation analysis showed that the AMS score was negatively correlated with the heart rate only at 7 minutes after inhalation of hypoxia gas, and the correlation coefficient r was -0.1776. CONCLUSIONS: The significance of AMS in the prediction of AMS in the plateau of 36 5 8 m simply by using hypoxia and breath-hold reaction may be limited.