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子宫内膜癌是妇科常见的三大恶性肿瘤之一,严重威胁女性的生活和健康。子宫内膜肿瘤干细胞与子宫内膜肿瘤的发生、发展、转移和复发密切相关,因而可能是导致子宫内膜肿瘤治疗失败的主要原因。目前已成功分离和鉴定出子宫内膜干细胞。子宫内膜肿瘤干细胞可能来源于正常子宫内膜干细胞或其分化的细胞,对子宫内膜肿瘤干细胞的表面标记物及其分离和鉴定方法的探索已取得一定成果。综述子宫内膜肿瘤干细胞的研究进展。
Endometrial cancer is one of the three most common gynecological malignant tumors, a serious threat to women’s lives and health. Endometrial cancer stem cells are closely related to the occurrence, development, metastasis and recurrence of endometrial cancer, which may be the main reason for the failure of endometrial cancer treatment. Endometrial stem cells have been successfully isolated and identified. Endometrial cancer stem cells may originate from normal endometrial stem cells or their differentiated cells. The exploration of the surface markers of endometrial cancer stem cells and their isolation and identification methods have yielded some results. Review of Research Progress of Endometrial Tumor Stem Cells.