论文部分内容阅读
目的观察单唾液酸四己糖神经节苷脂钠注射液联合高压氧治疗新生儿缺氧缺血性脑病的临床疗效。方法将184例缺氧缺血性脑病患儿随机分为研究组(92例)和对照组(92例)。研究组患者采用单唾液酸四己糖神经节苷脂钠注射液联合高压氧治疗,对照组采用常规治疗联合高压氧治疗。比较并评价这2组患者治疗后临床症状改变情况及总有效率。结果研究组意识恢复时间、肌张力恢复时间、吸吮能力恢复时间、原始反射恢复时间均明显短于对照组,总有效率明显高于对照组,差异均有统计学意义(P<0.05)。结论单唾液酸四己糖神经节苷脂钠注射液联合高压氧治疗新生儿缺氧缺血性脑病具有更好的临床疗效,可在临床广泛推广。
Objective To observe the clinical effect of monosialotetrahexosyl ganglioside sodium injection combined with hyperbaric oxygen on neonatal hypoxic-ischemic encephalopathy. Methods 184 children with hypoxic ischemic encephalopathy were randomly divided into study group (92 cases) and control group (92 cases). Patients in the study group were treated with monosialotetrahexosyl ganglioside sodium injection combined with hyperbaric oxygen. The control group was treated with conventional therapy combined with hyperbaric oxygen. Compare and evaluate the clinical symptoms and the total effective rate in these two groups after treatment. Results The recovery time, muscle tone recovery time, sucking ability recovery time and original reflex recovery time were significantly shorter in the study group than those in the control group. The total effective rate was significantly higher than that in the control group (P <0.05). Conclusion Monosialotetrahexosyl ganglioside sodium injection combined with hyperbaric oxygen treatment of neonatal hypoxic-ischemic encephalopathy has better clinical efficacy, can be widely promoted in the clinic.