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为进一步提高麻疹监测工作质量 ,对重庆市 2 0 0 0年麻疹实验室监测结果进行了分析。共检测了 186份疑似麻疹病例血清标本 ,其中爆发病例标本 16 6份 ,散发病例标本 2 0份 ,麻疹IgM抗体阳性数分别为 92份和 14份。两起爆发病例的 2 0份麻疹IgM抗体阴性标本中 ,11份风疹IgM抗体阳性 ,确证为风疹爆发。 6个年龄组 5 2 9份标本麻疹IgG抗体平均阳性率为 85 0 7% ,8～ 2 3月龄阳性率为 81 16 %。从 10份咽拭子标本中分离出 5株麻疹病毒 ,经核酸序列分析鉴定 ,均为H1基因型。建议对疑似麻疹爆发病例同时进行麻疹和风疹的血清学诊断 ;麻疹疫苗的第 2次接种应提前至 18月龄 ;在加速控制麻疹阶段实验室诊断显得更为重要。
In order to further improve the quality of measles monitoring work, the monitoring results of measles laboratory in Chongqing in 2000 were analyzed. A total of 186 serum samples of suspected measles cases were detected, of which 16 were outbreaks and 20 were sporadic cases. The positive numbers of measles IgM antibodies were 92 and 14, respectively. Of the 20 cases of measles IgM antibody-negative specimens from two outbreak cases, 11 were positive for rubella IgM antibody and confirmed as a rubella outbreak. The average positive rate of measles IgG antibody in 5 2 9 samples of 6 age groups was 85 0 7%, and the positive rate of 8 ~ 2 3 months old was 81 16%. Five strains of measles virus were isolated from 10 throat swab specimens and identified by nucleic acid sequence analysis, all of which were of the H1 genotype. It is recommended that serological diagnosis of measles and rubella should be conducted concurrently with suspected cases of measles outbreaks; the second vaccination of measles vaccine should be advanced to 18 months of age; laboratory diagnosis in the accelerated control of measles is even more important.