论文部分内容阅读
目的:探讨血清肌钙蛋白Ⅰ(cTnI)及心肌酶谱在毒蛇咬伤患者心肌损伤中的临床意义。方法:将328例毒蛇咬伤患者的临床资料按照入院时的病情分为:轻型229例、重型71例及危重型28例;按蛇毒类型分类:神经毒12例,血循毒14例,混合毒302例。比较各组间的心肌酶谱与cTnI的变化。结果:重型组心肌酶谱较轻型组明显升高(P<0.01),而cTnI无显著差异;危重型组心肌酶谱、肌钙蛋白Ⅰ较轻型组和重型组均明显升高(P<0.01)。血循毒和混合毒组心肌酶谱和肌钙蛋白Ⅰ较神经毒组明显升高(P<0.01)。结论:cTnI检测可反映毒蛇咬伤患者心肌的损伤,且比心肌酶谱更有临床价值。
Objective: To investigate the clinical significance of serum cardiac troponin Ⅰ (cTnI) and myocardial enzymes in the myocardial injury of snakebite patients. Methods: The clinical data of 328 snakebite patients were divided into two groups based on the condition of admission: 229 cases of light type, 71 cases of heavy type and 28 cases of critical type. According to the types of snake venom, 12 cases were neurotoxic and 14 cases were mixed with blood poisoning Toxic 302 cases. The changes of myocardial enzymes and cTnI were compared between groups. Results: The myocardial enzymes of severe group were significantly increased (P <0.01), but there was no significant difference of cTnI; the levels of myocardial enzymes and troponin Ⅰ were significantly higher in severe group than those in mild group (P <0.01) ). Compared with neurotoxic group, myocardial enzymes and troponin I in blood poisoning and mixed poisoning groups were significantly increased (P <0.01). Conclusion: The detection of cTnI can reflect the damage of myocardium in patients with venomous snake bite and is more clinical value than the myocardial enzyme spectrum.