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目的:比较多糖铁复合物胶囊和生血宁片纠正维持性血液透析(MHD)患者肾性贫血的疗效。方法:选取2016年4月至6月本院透析中心MHD治疗且满足缺铁性贫血标准的患者，以随机区组设计法分为多糖铁复合物组和生血宁组，接受3个月治疗。在治疗前及治疗后的第1、2、3个月分别检测血常规、铁代谢指标，并记录不良反应发生率，观察和比较两组治疗达标率，并对两组患者行成本-效益分析。结果:每组有30例患者完成随访。3个月治疗后，两组患者血常规和铁代谢指标均较前改善(n P<0.05)。与生血宁组相比，多糖铁复合物组贫血纠正显效率、血红蛋白、转铁蛋白饱和度、血清铁蛋白较高，重组人促红细胞生成素使用量较少(n P0.05)。成本效益分析提示，使用多糖铁复合物治疗贫血有更低的成本和更高的效益(n P<0.05)。n 结论:多糖铁复合物胶囊能较好地纠正贫血和改善铁代谢，成本效益比较低，可有效减少医保支出，对于MHD患者是良好的口服补铁方式。“,”Objective:To compare the therapeutic effect of polysaccharide iron complex capsule and Shengxuening tablet on renal anemia in maintenance hemodialysis (MHD) patients.Methods:Patients who received MHD treatment from April to June 2016 in our dialysis center and met the criteria for iron deficiency anemia were block-randomly divided into two groups: the polysaccharide-iron complex group and the Shengxuening group. Blood routine, iron metabolism biomarkers and biochemical exams were measured before treatment and at the 1st, 2nd and 3rd months after treatment, and the incidence of adverse reactions were recorded. The compliance rate of the two groups was observed and compared, and the block-randomized-statistical methods were used to compare the clinical data of the two groups before and after treatment, and cost-benefit analysis was also conducted.Results:Thirty patients in each group completed follow-up. After three months of treatment, the blood routine and iron metabolism indicators of the two groups were improved. Compared with the Shengxuening group, the polysaccharide iron complex group had higher therapeutic efficiency, and the levels of hemoglobin, transferrin saturation and serum ferritin were higher, and lower use of recombinant human erythropoietin (n P<0.05). The other indexes such as red blood cell (RBC), hematocrit (HCT) levels and the effective rate of anemia correction, the effective rate of iron therapy, the effective rate of iron therapy between the two groups were similar. Cost-benefit analysis suggested that the use of polysaccharide iron complexes to treat anemia has lower costs and higher benefits (n P<0.05).n Conclusions:Polysaccharide iron complex capsule can better correct anemia and improve iron metabolism, and has low cost-effectiveness, which can effectively reduce medical insurance expenditure. It is a good iron supplementing method in addition to intravenous iron supplement.