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目的观察1周胰岛素泵治疗对2型糖尿病血脂谱的影响。方法选取50例2型糖尿病患者,予胰岛素泵强化治疗1周,动态观察治疗前后血糖、血脂谱变化。结果 1周胰岛素泵治疗后,患者空腹血糖和餐后血糖较前显著下降(P<0.001)。同时,患者总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)和载脂蛋白B水平显著下降(P<0.001),TC和LDL-C的达标率显著升高(P<0.05),而甘油三酯、高密度脂蛋白胆固醇、载脂蛋白A无明显改善。结论 1周胰岛素泵强化治疗显著降低2型糖尿病患者血糖同时可以部分改善患者血脂代谢异常。
Objective To observe the effect of 1-week insulin pump on the blood lipid profile of type 2 diabetic patients. Methods Fifty patients with type 2 diabetes mellitus were selected and treated with insulin pump for 1 week. The changes of blood glucose and lipid profile were observed before and after treatment. Results After 1 week of insulin pump treatment, fasting blood glucose and postprandial blood glucose decreased significantly (P <0.001). At the same time, the levels of total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and apolipoprotein B were significantly decreased (P <0.001) and the compliance rates of TC and LDL- The triglycerides, high-density lipoprotein cholesterol, apolipoprotein A no significant improvement. Conclusion One-week intensive insulin treatment can significantly reduce blood glucose in patients with type 2 diabetes mellitus at the same time can partially improve the patient’s blood lipid metabolism.