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用ＤＥＡＥ－ｓｅｐｈａｄｅｘＡ－５０微型柱层析结合分光光度法测５１例急性脑血管病（ＡＣＶＤ）和２０例正常人血清和脑脊液（ＣＳＦ）肌酸激酶（ＣＫ）及其脑型同工酶（ＣＫＢＢ）活性（统称ＣＫ活性）。结果发现：中风组ＣＫ活性显著高于正常组（Ｐ＜０．００１）。脑出血ＣＫ活性有高于脑梗塞的趋势。除血清中ＣＫ活性外，病程≤３ｄ组ＣＫ活性高于＞３ｄ组（Ｐ＜０．０１）。病情重、病灶大者，ＣＫ活性较高。中风急性期，尤其病程３ｄ内测血、ＣＳＦ中ＣＫ活性有助于判断病灶大小及病情严重程度
51 cases of acute cerebrovascular disease (ACVD) and 20 cases of normal human serum and cerebrospinal fluid (CSF) creatine kinase (CK) and its brain-type isoenzyme (CKBB) were detected by DEAE-sephadexA-50 microcolumn chromatography and spectrophotometry ) Activity (collectively CK activity). The results showed that CK activity in stroke group was significantly higher than that in normal group (P <0.001). The activity of CK in cerebral hemorrhage is higher than that of cerebral infarction. In addition to serum CK activity, duration of disease less than 3d group CK activity> 3d group (P <0.01). Serious illness, lesions, CK activity higher. The acute phase of stroke, especially the duration of blood test within 3 days, CK activity in CSF helps determine the size of the lesion and the severity of the disease