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目的 研究二陈汤粉剂及二陈汤提取物的镇咳化痰作用。方法 应用二陈汤粗粉与二陈汤提取物观察对小鼠氨水致咳作用及呼吸道酚红排泄作用的影响。结果 粉剂和提取物均能抑制氨水的致咳作用及增加小鼠呼吸道酚红的排泄 ,表明二陈汤具有镇咳祛痰作用 ;在含生药量近似的情况下 ,提取物的上述药理作用较显著。结论 二陈汤剂型改革可提高其药理效应
Objective To study the antitussive and expectorant effects of Erchentang powder and Erchentang extract. Methods The effect of Erchentang crude powder and Erchentang extract on the ammonia-induced cough and the excretion of phenol red in the respiratory tract were observed. Results Both powders and extracts could inhibit the coughing effect of ammonia and increase the excretion of phenol red in the respiratory tract of mice, indicating that Erchentang has antitussive and expectorant effects. The above pharmacological effects of extracts were comparable when the amount of crude drug was similar. Significant. Conclusion Erchen decoction reform can improve its pharmacological effect