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目的:本研究应用原有评定指标综合分析,初步探讨创伤性截肢手术适应证以及手术方法的实施。方法本研究对自2005年8月~2013年12月来本院81例肢体严重创伤骨折患者的病史、年龄、体检、治疗时间及方法进行综合性分析。患者入院后急诊行全面体检以及X线片检查。81例伤者中,累及右侧肢体52例,左侧肢体29例,单纯损伤23例,复合损伤58例。开放伤按Gustilo等的分类标准,在本组中Ⅲa型骨折2例,Ⅲb型骨折18例,Ⅲc型骨折61例,合并休克10例,均有不同程度的足背动脉及胫后动脉搏动减弱或消失。结果根据Gregory的MESI评分法观点,评分>20是截肢的相关指征。本组患者评分>20者患肢52肢,截肢46例,截肢率为88.5%;评分20, there were 46 cases of amputation (88.5%);In the group of 29 cases of which the patients’s score<20, there were 3 cases of amputation (10.3%), carrying out a significant difference (P<0.01). In the 49 cases of amputation, theirMESS value was 7-13, with an average of 9.095 points, and the non-amputation group reflected MESS 2~7, with an average of 3.892 points;there is statistically significant difference in between the limb amputation group and the non-amputation group with P value<0.01. 47 limb amputation took place in a total of 61 cases of leg typeⅢC open fracture of limb, with an amputation rate of 77%. Conclusion Even though amputation is considered as a destructive operation, it has to be done when necessary with scientific standard. Not only such an operation helps save the patients’life but restore their physical and mental rehabilitation. Referring to all kinds of standards for amputation, all the factors have to be given full consideration before the operation.