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目的：探讨N-甲酰肽受体（N-formylpeptide receptor,FPR）基因单核苷酸多态性（single nucleotide polymor-phism,SNP）与侵袭性牙周炎（aggressive periodontitis,AgP）易感性的关系。方法：选择AgP患者94例,健康对照者73例。抽取前臂静脉血,提取基因组DNA,PCR扩增目的基因片段,用变性高效液相色谱（denature high perfor-mance liquid chromatography,DHPLC）结合DNA测