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1 概述 纤溶系统负责清除循环血液中的纤维蛋白,包括一个无活性的酶原即纤溶酶原,此酶原被纤溶酶原激活物激活成纤溶酶,纤溶酶降解纤维蛋白及细胞外基质蛋白。纤溶系统的抑制可在两个水平上进行:一是在纤溶酶水平,主要是a2-抗纤溶酶(a2-AP);另一个是在纤溶酶原激活物水
1 Overview The fibrinolytic system is responsible for the removal of circulating blood fibrin, including an inactive zymogen plasminogen, which is activated by plasminogen activator plasmin, fibrinolytic degradation of fibrin and Extracellular matrix protein. Inhibition of the fibrinolytic system can be performed at two levels: one at plasmin level, predominantly a2-antiplasmin (a2-AP); the other at fibrinogen activator water