目的探讨地佐辛复合丙泊酚用于妇科宫腔镜检查及治疗麻醉中的效果和安全性。方法选取200例,ASA分级为Ⅰ~Ⅱ级,行宫腔镜检查及治疗的妇科患者,随机分为两组:地佐辛复合丙泊酚组(A组,n=100),芬太尼复合丙泊酚组(B组,n=100)。观察并记录两组患者宫腔镜检查治疗前及麻醉前(T0)、麻醉后2 min(T1)、扩宫颈时(T2)、宫腔镜检查治疗后(T3)、清醒后4~5 min(T4)时BP、SpO2、HR,同时记录两组患者呼吸抑制的发生例数、术后疼痛的程度和丙泊酚的用量。结果两组宫腔镜检查治疗前及麻醉前BP、HR、SpO2比较差异无统计学意义(P>0.05);T1与T0时间点:BP、HR下降差异有统计学意义(P<0.05);SpO2变化无显著性(P>0.05);A组与B组各检测记录时点比较差异无统计学意义(P>0.05);两组麻醉起效时间、麻醉苏醒时间及呼吸抑制例数差异无统计学意义(P>0.05);应用丙泊酚总量和宫腔镜检查治疗后疼痛的例数,B组多于A组,差异有统计学意义(P<0.05)。结论地佐辛与丙泊酚复合麻醉在妇科宫腔镜检查及治疗中效果满意,适宜应用。 Objective To investigate the effect and safety of dezocine combined with propofol in gynecological hysteroscopy and anesthesia. Methods A total of 200 gynecologic patients undergoing hysteroscopy and treatment were divided into two groups: dezocine combined with propofol group (group A, n = 100), fentanyl combination Propofol group (B group, n = 100). Observe and record two groups of patients before hysteroscopy and before anesthesia (T0), 2 min after anesthesia (T1), cervical dilatation (T2), hysteroscopy (T3) after treatment, 4 to 5 min after awake (T4) BP, SpO2, HR, while recording the number of cases of respiratory depression in both groups, the degree of postoperative pain and the amount of propofol. Results There was no significant difference in BP, HR and SpO2 between the two groups before treatment and before anesthesia (P> 0.05). The difference between T1 and T0 was significant (P <0.05). There was no significant difference in SpO2 between the two groups (P> 0.05). There was no significant difference in the recording time points between group A and group B (P> 0.05). There was no difference between the two groups in anesthesia onset time, anesthesia recovery time and respiratory depression Statistical significance (P> 0.05). The total number of cases treated with propofol and hysteroscopy was significantly higher in group B than in group A (P <0.05). Conclusion Dezocine and propofol combined anesthesia in gynecological hysteroscopy and treatment of satisfactory results, suitable for application.