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来自62个无亲缘关系家庭的158例年龄10岁以上患有可查证的常染色体显性型多囊肾(PKD——以下同)的病人中有46例(29%)发现肝囊肿.有PKD而肾囊肿未被察觉出来的病人没有一个发现肝囊肿.肝囊肿的罹患率随年龄增加和肾小球滤过率的降低而增加.临床和实验室的研究说明,常染色体显性型PKD病人的多发性肝囊肿是良性情况,简直很少引起肝功能损害和门静脉高压.
Forty-six (29%) of the 158 patients with proven autosomal dominant polycystic kidney disease (PKD) who were over age 10 from 62 unrelated families were found to have hepatic cysts with PKD None of the patients with renal cysts were found to have hepatic cysts.The incidence of hepatic cysts increased with age and decreased glomerular filtration rate.Clinical and laboratory studies have shown that patients with autosomal dominant PKD Multiple hepatic cysts are benign and rarely cause liver dysfunction and portal hypertension.