肺癌的侵袭转移的过程是多步骤的、序贯的、非常复杂的,其包括:原发肿瘤的血管化、肿瘤细胞脱离原发瘤、对基底膜和其他细胞基质的降解、进入脉管、运行到靶器官停泊、穿出脉管进入组织及继续生长形成转移瘤。基质金属蛋白-9(MMP-9)是一类细胞外蛋白水解酶,可降解细胞外基质(EC The process of lung cancer invasion and metastasis is multi-step, sequential and very complex and includes: vascularization of primary tumors, tumor cells detaching from primary tumors, degradation of basement membranes and other cellular matrices, entry into vessels, Run to the target organ moorings, out of the vessel into the tissue and continue to grow to form metastases. Matrix Metalloprotein-9 (MMP-9) is a type of extracellular proteolytic enzyme that degrades extracellular matrix (EC