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英国一家公司研制出一种用于药物吸收研究的遥控式药物投递囊体。这种名为Enterion药囊的新产品由费顿研究公司(Phaeton Research)研制,目前正由其姊妹公司Pharmaceutical Profiles制药公司使用,该公司是药物早期实验开发公司)。 根据设计,这种药囊可在胃肠道内的靶向位置准确地释放出药物。研究人员可测得药物在胃肠内不同部位的吸收程度。 药囊在体内通过射频信号启动后,能驱动一弹簧控制的塞栓而释出囊中药物(药囊为圆柱形,长32mm,直径为9mm)。药囊在胃肠道内的位置由γ闪烁扫描仪进行追踪,药物中所含的放射性示踪同位素能显示药物在胃肠中的情况。空囊体最后被排泄出体外。
A British company has developed a remote controlled drug delivery capsule for drug absorption studies. The new product, Enterion Sachet, was developed by Phaeton Research and is currently being used by its sister company Pharmaceutical Profiles Pharmaceuticals, an early drug development company. The sachet is designed to accurately release the drug at targeted locations in the gastrointestinal tract. Researchers can measure the absorption of drugs in different parts of the gastrointestinal tract. After the sachet is activated in vivo by radio frequency signals, it can drive a spring-controlled stopper and release the drug in the capsule (sachet cylindrical, 32 mm long and 9 mm diameter). The location of the sachet in the gastrointestinal tract is tracked by a gamma scintigraphy, and radioactive tracer isotopes contained in the drug can show the drug in the gastrointestinal tract. Empty balloon body was finally excreted.