目的观察非洛地平缓释片对老年高血压病的治疗效果、不良反应及对患者代谢的影响。方法选择30例老年高血压病患者,每日早晨顿服非洛地平缓释片2.5mg,采用逐渐增量的方法,最大剂量为10mg/d,疗程6周。比较治疗前后患者血压情况,观察用药前后血生化指标。结果服药6周后,血压明显下降与治疗前相比,差异有统计学意义(P<0.05)。30例患者中显效21例70%,有效6例(20%),总有效率达90%。治疗前后空腹血糖血脂、肾功能及电解质无显著变化(P>0.05),不良反应发生率为10%。 Objective To observe the effect of Felodipine extended-release tablets on senile hypertension, adverse reactions and the effects on patients’ metabolism. Methods Thirty elderly patients with essential hypertension were enrolled in this study. The daily dose of felodipine sustained-release tablets was 2.5 mg. The maximum dose was 10 mg / d for 6 weeks. Before and after treatment of patients with blood pressure, blood biochemical indicators before and after treatment. Results After 6 weeks of medication, the blood pressure decreased significantly compared with that before treatment, the difference was statistically significant (P <0.05). Among the 30 patients, 21 cases were markedly effective, 70% effective, and 6 were effective (20%). The total effective rate was 90%. Fasting blood glucose, blood lipid, renal function and electrolytes had no significant changes before and after treatment (P> 0.05), and the incidence of adverse reactions was 10%.