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目的：为阐明大山区（云南和四川省）有钉螺而无日本血吸虫病流行地区（简称：有螺无病地区）钉螺在流行病学中的意义及为制定防治方案提供依据。方法：选择大山区４个有代表性有螺无病村的钉螺，以所在省的日本血吸虫毛蚴在实验室进行群体感染，钉螺与毛蚴比例分别为１∶４０和１∶９０。结果：４个有螺无病村的钉螺均能为日本血吸虫毛蚴感染，其中，四川省两个有螺无病村钉螺体内的日本血吸虫毛蚴可发育至尾蚴阶段。结论：云南、四川省有螺无病地区钉螺在适宜的环境和一定数量的传染源的条件下可以为所在省的血吸虫毛蚴感染，大山区有螺无病地区为潜在的日本血吸虫病流行区，应加强对这类地区日本血吸虫传染源输入的监测工作。
OBJECTIVE: To provide a basis for elucidating the importance of snail in the mountainous areas (Yunnan and Sichuan Provinces) without snail schistosomiasis endemic areas (abbreviated: snail disease-free areas) in epidemiology and to develop prevention and treatment plans. Methods: Four snails were selected in the mountainous area to study the infection of Schistosoma japonicum mirabilis in the laboratory. The ratio of snails and miracles were 1:40 and 1:90, respectively. Results: All 4 snails infected with snail were able to infect Schistosoma japonicum. Among them, Schistosoma japonicum miracidia could be developed to two stages in cercariae. CONCLUSIONS: In Yunnan and Sichuan Province, snail moths infected with Schistosoma japonicum may be the province of Schistosoma japonicum under the suitable environment and a certain number of infection sources. The snail disease-free area in the mountainous area is the potential epidemic area of Schistosoma japonicum, The monitoring of the input of Schistosoma japonicum source in such areas should be strengthened.