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目的探讨职业紧张对超净车间女工生殖内分泌的影响及机制。方法选取具有代表性的电子行业超净车间女工1123名作为研究对象,采用职业紧张调查表(OSI)、生殖调查表和月经卡调查研究对象的职业紧张和生殖内分泌现状,收集有效问卷860例,根据紧张程度分为3组,比较3组月经异常情况及血清睾酮(T)和催乳素(PRL)浓度水平。结果3组出现月经异常的比例分别为86.9%、71.8%、57.7%,差异具有统计学意义;随着紧张程度的生高,T、PRL的水平也随之升高,差异有统计学意义(P<0.05)。结论职业紧张可对超净车间女工生殖内分泌功能产生不良影响,且随着紧张程度的增加而升高。
Objective To investigate the effect and mechanism of occupational stress on reproductive endocrine of female workers in a clean room. Methods A total of 1123 female workers in the ultra-clean workshop of the electronics industry were selected as the research objects. Occupational stress and reproductive endocrine status were investigated using occupational stress questionnaire (OSI), reproductive questionnaire and menstrual card. Eighty-six valid questionnaires were collected, According to the degree of stress, the patients were divided into 3 groups, and the abnormal menstruation and serum testosterone (T) and prolactin (PRL) levels were compared among the 3 groups. Results The proportions of abnormal menstruation in 3 groups were respectively 86.9%, 71.8% and 57.7%, the difference was statistically significant. With the height of stress, the levels of T and PRL also increased, the difference was statistically significant ( P <0.05). Conclusion Occupational stress may have an adverse effect on the reproductive and endocrine function of women workers in a clean workshop, and increase with the increase of stress level.