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人至老年,由于内、外因素影响,全身各器官组织结构均发生变化,因此,老年患者对药物的敏感性和耐受性也相应地发生改变,临床医生在给老年病人用药时,应权衡药物的利弊,适时合理用药,才能提高疗效、避免药物不良反应和事故的发生。本文就老年人的生理、病理特点及用药原则作一概述。一、老年人生理病理特点和药物的关系 1.中枢神经系统:老年人脑萎缩,大脑皮层及小脑神经细胞均有不同程度减少,脑血流量减少,脑
People to the elderly, due to internal and external factors, changes in the structure of various organs of the body, therefore, the elderly patients on the sensitivity and tolerance of the drug has changed accordingly, clinicians should be weighed in the elderly patients medication The pros and cons of drugs, timely and appropriate medication, in order to improve the curative effect, to avoid adverse drug reactions and accidents. This article gives an overview of the physiological, pathological features and medication principles of the elderly. First, the physiological characteristics of the elderly and the relationship between drugs 1. Central Nervous System: Senile brain atrophy, cerebral cortex and cerebellar nerve cells were reduced to varying degrees, decreased cerebral blood flow, brain