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目的:观察急性脑梗死常规治疗与加用依达拉奉之间治疗效果的差别。方法:70例急性脑梗死患者随机分为治疗组和对照组,每组各35例。2组均常规使用生理盐水250mL与丹参注射液30mL静脉滴注,qd,治疗组加用依达拉奉30mg静脉点滴,bid。2周后分别进行临床疗效与ESS评定。结果:治疗组总有效率达85.7%,显效率为57.1%,而对照组分别为54.3%和37.1%,2组比较差异有显著性(P<0.01和P<0.05)。2周后ESS评分治疗组明显优于对照组(P<0.01)。结论:依达拉奉治疗急性脑梗死具有实用,安全性高,不良反应少,疗效好等优点。其强大的自由基清除功能所起到的神经保护作用,对急性脑梗死患者非常有益。
Objective: To observe the difference between the curative effect of conventional treatment of acute cerebral infarction and add edaravone. Methods: Seventy patients with acute cerebral infarction were randomly divided into treatment group and control group, 35 cases in each group. 2 groups were routinely used saline 250mL and 30mL Danshen injection intravenously, qd, the treatment group with edaravone 30mg intravenously, bid. After 2 weeks, respectively, clinical efficacy and ESS assessment. Results: The total effective rate was 85.7% in the treatment group, markedly effective rate was 57.1%, while the control group was 54.3% and 37.1% respectively. There was significant difference between the two groups (P <0.01 and P <0.05). After 2 weeks ESS score treatment group was significantly better than the control group (P <0.01). Conclusion: Edaravone has the advantages of being practical, safe, less adverse reactions and good curative effect in the treatment of acute cerebral infarction. Its powerful role of free radical scavenger neuroprotection, in patients with acute cerebral infarction is very useful.