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目的了解阳泉地区婴幼儿腹泻中轮状病毒感染的情况。方法收集阳泉市第一人民医院2005-07~2006-06底住院的腹泻患儿粪便标本130份,采用胶体金法,检测轮状病毒。结果130份粪便标本中,58份检测到A组轮状病毒,阳性检出率为44.6%,未检出B组及C组轮状病毒。58份中,2岁以下婴幼儿53例,占91.4%,平均发病年龄为13.3个月。社区感染为41例(70.7%),院内感染17例(29.3%)。临床表现发热、呕吐、腹泻、脱水,部分伴心肌酶学异常,CK-MB升高,1例死亡。发病季节2005-11~2006-01阳性检出率达50%以上。结论A组轮状病毒是阳泉地区2005-07~2006-06 2岁以下婴幼儿腹泻病的主要病原,2岁以下婴幼儿是轮状病毒的易感人群,以11月份至第2年1月份为流行高峰。临床以发热、呕吐、腹泻为主,心肌受累较广泛,严重者可导致死亡。
Objective To understand the rotavirus infection in infant diarrhea in Yangquan area. Methods 130 cases of diarrhea stool samples from the first People’s Hospital of Yangquan City from the end of 2005-07 to 2006-06 were collected. The colloidal gold method was used to detect rotavirus. Results Of the 130 stool samples, 58 samples of group A were positive for rotavirus A, with a positive rate of 44.6%. No group B and C rotavirus were detected. Among 58 cases, 53 infants under 2 years old accounted for 91.4% with an average age of onset of 13.3 months. Community-based infections were 41 (70.7%) and nosocomial infections (29.3%). Clinical manifestations of fever, vomiting, diarrhea, dehydration, some with abnormal myocardial enzymes, CK-MB increased, 1 patient died. Incidence season 2005-11 ~ 2006-01 positive rate of 50% or more. Conclusions Group A rotavirus is the main pathogen of diarrhea in infants younger than 2 years from 2005-07 to 2006-06 in Yangquan area. The infants younger than 2 years old are rotavirus susceptible persons. From November to January of the second year For the popular peak. Clinical fever, vomiting, diarrhea, myocardial involvement is more extensive, severe cases can lead to death.