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目的探讨他汀类药物对缺血性卒中患者血超敏C-反应蛋白水平的影响。方法将70例新发缺血性脑卒中患者随机分为他汀治疗组和对照组,治疗组入院后给予他汀类药物,对照组不给予,其余治疗完全同治疗组。观察两组血超敏C-反应蛋白变化。结果他汀治疗组血超敏C-反应蛋白水平和对照组比较差异有统计学意义(P<0.05)。结论他汀类药物除了常规用于降血脂治疗,还可降低缺血性脑血管病患者超敏C-反应蛋白水平。
Objective To investigate the effect of statins on serum C-reactive protein in patients with ischemic stroke. Methods Seventy patients with new-onset ischemic stroke were randomly divided into statin group and control group. The patients in the treatment group were given statins after admission. The control group was not given. The rest of the treatment group was the same as the treatment group. The changes of blood hypersensitivity C-reactive protein were observed. Results Compared with the control group, the serum levels of C-reactive protein in statin group were significantly different (P <0.05). Conclusion Statins can reduce the level of high-sensitivity C-reactive protein in patients with ischemic cerebrovascular disease in addition to routine treatment for lowering blood lipids.