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动脉粥样硬化病灶的形成和血流力学因素的关系自魏尔啸以来就一直受到重视。粥样硬化病灶具有在一定区域分布的倾向,即在血管分叉和弯曲处等局部应力作用强的部位易于发生。给家兔静注伊文思兰观察主动脉的色素掺入时.在饲胆固醇家兔的主动脉上可见到与脂质沉积大体相同的血管分叉处附近的浓染。
The relationship between the formation of atherosclerotic lesions and hemodynamic factors has been valued since Weier Xiao. Atherosclerotic lesions have a tendency to be distributed in a certain area, that is, sites where local stress is strong such as at a bifurcation and a bend of a blood vessel tend to occur. When intravenous injection of Evans blue was observed in rabbits to observe pigment dilation in the aorta, staining near the bifurcation of blood vessels was observed on the aorta of rabbits fed cholesterol.