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本文对176例健康成人和126例慢性阻塞性肺气肿患者测定了最大用力吸气流量—容积曲线(MFIV)和75例同时测定了MFIV和最大用力吸气口腔压(MIMP)。结果表明:与健康组比较,肺气肿各组MFIV各段流量均显著降低(P<0.01)和吸气时间显著延长(P<0.01),且随肺气肿的加重MFIV呈逐渐降低趋势。RV/TLC%与肺气肿组MFIV各段流量呈负相关(P<0.01),与吸气时间呈正相关(P<0.01)。75例MFIV各段流量与MIMP显著相关(P分别<0.05及0.01)。以上结果表明,MFIV可能是反映吸气肌功能的简便指标。
In this study, maximum forced inspiratory flow volume-volume curve (MFIV) and 75 simultaneous MFIV and maximum impactive oral pressure (MIMP) were measured in 176 healthy adults and 126 patients with COPD. The results showed that compared with the healthy group, the flow of MFIV in each group was significantly decreased (P <0.01) and inspiratory time significantly prolonged (P <0.01), and with the increase of emphysema MFIF was Gradually reduce the trend. The RV / TLC% was negatively correlated with the flow of MFIV in emphysematous group (P <0.01), and positively correlated with inspiratory time (P <0.01). Flows in 75 MFIV sections were significantly associated with MIMP (P <0.05 and 0.01, respectively). The above results indicate that MFIV may be a simple indicator of inspiratory muscle function.