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美尼尔氏病的主要病理特点是膜迷路膨胀,一般以蜗管及球囊的膨胀为主。作者通过15例美尼尔氏病患者的颞骨标本,观察椭圆囊及囊半规管的体积和长度,并注意体积和长度的变化与前庭、听力等症状的关系。颞骨标本经固定、脱钙、包埋等处理后作成厚20μm的水平切片,每隔十张切片,作光学显微镜检查,并以计算机作图象处理后分别测得椭圆囊、各半规管及椭圆囊+半规管的容积和长度。另以对侧耳及正常耳各15例作为对照组。测量结果:(1)正常耳左、右耳膜迷路的容积和长度无明显差别。(2)内淋巴积水者病耳椭圆囊之容积比正常耳及对侧耳增大35%,椭圆囊+半规管的容积比正常及对侧耳增大20%(t值>0.95,有统计学意义)。(3)病耳椭
The main pathological features of Meniere’s disease is labyrinthine labyrinthine expansion, which is generally dominated by the expansion of the cochlear duct and balloon. Through the temporal bone specimens of 15 cases of Meniere’s disease, the authors observed the volume and length of the oval capsule and the capsule semicircular canal, and noted the relationship between changes in volume and length and the symptoms of vestibular and hearing. Temporal bone specimens were fixed, decalcified, embedding and other processed to make a thickness of 20μm slice, every 10 slices for optical microscopy and computer image processing were measured after the oval capsule, the semicircular canal and the oval capsule + Semi-regulatory tube volume and length. Another contralateral ear and normal ears of 15 cases as a control group. Measurement results: (1) There is no significant difference in the volume and length of labyrinthine left and right ear labyrinth. (2) The volume of diseased ear oval sac in patients with endolymphatic fluid increased by 35% than that of normal ears and contralateral ears, and the volume of oval sacs + semicircular canals increased by 20% (t> 0.95) compared with the normal and contralateral ears ). (3) sick ear oval