论文部分内容阅读
目的了解不同途径使用生姜液的抗运动病效果并比较生姜与东莨菪碱和山莨菪碱抗运动病作用的强弱。方法给大鼠旋转刺激，诱发异嗜高岭土行为（按高岭土摄食量判定运动病轻重程度），观察各药剂对大鼠异嗜高岭土行为的抑制情况。结果腹腔注射生姜液的大鼠，经旋转刺激后高岭土摄入量明显低于灌胃给药的大鼠。生姜与抗胆碱药的抗运动病效果无显著差异，而东莨菪碱与山莨菪碱的抗运动病作用强度相当。结论腹腔注射生姜液的抗运动病作用强于灌胃给药。提示生姜抗运动病作用除与其对胃肠的直接作用有关外，可能还有其它作用机制
Objective To understand the anti-motion effects of ginger solution in different ways and compare the anti-motion effects of ginger, scopolamine and anisodamine. Methods The rats were subjected to rotational stimulation to induce heterophilic kaolin (the severity of motion sickness was determined according to the amount of kaolin ingested), and the inhibitory effect of each agent on the behavior of heterophilic kaolin in rats was observed. The results of intraperitoneal injection of ginger liquid rats, after rotary stimulation kaolin intake was significantly lower than the intragastric administration of rats. Ginger and anticholinergic anti-motion sickness effect no significant difference, and scopolamine and anisodamine anti-motion sickness intensity quite. Conclusion Intraperitoneal injection of ginger solution anti-motion sickness stronger than intragastric administration. Tip Ginger anti-exercise disease role in addition to its direct effect on the gastrointestinal, there may be other mechanisms of action