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感染病毒后患者血清中干扰素的增多和外周血单核细胞(PBMs)的抗病毒状态的出现有关.干扰素抗病毒作用的机理之一是能产生2’-5’寡聚腺苷酸合成酶(2-5AS),从而影响病毒的复制.已有实验说明人PBMs中的2-5AS活性是检测体内干扰素含量较敏
Increased interferon levels in patients’ sera after infection with the virus are associated with the emergence of antiviral status of peripheral blood mononuclear cells (PBMs). One of the mechanisms by which antiviral effects of interferon can produce 2’-5’-oligoadenylate synthesis Enzyme (2-5AS), thus affecting the replication of the virus.Experiments have been shown that 2-5AS activity in human PBMs is the detection of interferon in vivo more sensitive