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目的了解沂水县健康人群麻疹免疫水平状况,为实现消除麻疹目标提供科学依据。方法随机采集本县常住和流动人口血清标本350份,采用酶联免疫吸附试验(ELISA)测定7个年龄组健康人群麻疹Ig G抗体。结果沂水县健康人群麻疹Ig G抗体总阳性率为92.29%,其中男性阳性率为92.66%;女性抗体阳性率为91.91%,不同性别抗体水平差别(χ2=0.07,P>0.05);20岁以上年龄组的抗体水低于其他年龄组(χ2=8.27,P<0.05);常住和流动人口之间的麻疹抗体水平差别(χ2=1.41,P>0.05)。结论沂水县15岁以下健康人群麻疹抗体水平处于较高状态,基本形成了有效的免疫预防屏障;20岁~年龄组麻疹Ig G抗体水平相对较低,应进一步加强该人群含麻疹成分疫苗的免疫接种工作。
Objective To understand the status of measles immunity in healthy population in Yishui County and provide a scientific basis for eliminating the measles target. Methods A total of 350 serum samples from resident and migrant population in this county were randomly collected and measles IgG antibodies were detected by enzyme-linked immunosorbent assay (ELISA) in seven age groups. Results The positive rate of measles Ig G antibody in healthy population was 92.29% in Yishui County, the positive rate was 92.66% in male and 91.91% in female. The antibody level of different sex was different (χ2 = 0.07, P> 0.05) Antibody levels in the above age groups were lower than those in other age groups (χ2 = 8.27, P <0.05). Measles antibody levels differed between resident and mobile population (χ2 = 1.41, P> 0.05). Conclusion The level of measles antibody in healthy population below 15 years old in Yishui County is in a high state, and an effective immunoprotective barrier is basically formed. The level of measles IgE antibody in 20-year-old age group is relatively low, and the measles-containing vaccine should be further strengthened Immunization work.