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在心肌梗死的周围有一个边缘缺血区,缺血区需氧与供氧之间的平衡可以改变实验性梗死的范围。增加心肌需氧量的因素能增加梗死的范围,而减少需氧量的因素能缩小梗死的范围。近期冠状动脉闭塞的狗,心得安可使其心外膜ST段的抬高恢复正常,ST段的改变可能与缩小狗的梗死范围有关。Shillingford等对一组急性心肌梗死后72小时内的病人静注心得宁20毫克,发现心前区抬高的ST段有所降低,因为心外膜ST段升高的程度是心肌细胞坏死的严重程度的指标,从而推想β-阻滞剂在改变梗死范围中起一定
There is a marginal ischemic area around the myocardial infarction, and the balance between aerobic and oxygen supply changes the range of experimental infarcts. Increased myocardial oxygen demand factors can increase the scope of infarction, and reduce oxygen demand factors can reduce the scope of infarction. Recent coronary occlusion of dogs, the experience of Ankang epicardial ST segment elevation can be restored to normal, ST segment changes may be related to the narrowing of the infarct size of dogs. Shillingford and other patients within a group of 72 hours after acute myocardial infarction, intravenous injection of 20 mg rather nausea, found in the precordial elevated ST segment decreased, because the level of epicardial ST segment elevation is a serious myocardial necrosis Extent of the index, suggesting that β-blockers in the infarction to change the scope of certain