血管内皮细胞具有调节血管紧张度、血管通透性及促进血管发生的作用。因此,内皮细胞功能障碍被认为是糖尿病所引起的慢性血管并发症发病的关键因素。但内皮细胞功能障碍也可受胰岛素抵抗的各种表现所影响,如:高血压、血脂紊乱和高糖血症等。因此,内皮细胞功能障碍可能与胰岛素 Vascular endothelial cells have the role of regulating vascular tone, vascular permeability and promoting angiogenesis. Therefore, endothelial cell dysfunction is considered as a key factor in the pathogenesis of chronic vascular complications caused by diabetes mellitus. However, endothelial dysfunction can also be affected by various manifestations of insulin resistance, such as: hypertension, dyslipidemia and hyperglycemia. Therefore, endothelial dysfunction may be associated with insulin