论文部分内容阅读
主动脉瓣狭窄是临床上比较常见的心脏瓣膜病,其主要的病因是主动脉瓣膜钙化。随着人口老龄化的加剧,钙化性主动脉瓣膜病的发病率也不断的增加,因此,过去20多年中,钙化性主动脉瓣膜狭窄一直被认为是一种退行性病变,然而随着近年的研究进展,大量的证据表明,钙化性主动脉瓣膜病是一个活跃的病理过程,其与动脉粥样硬化有相同的风险因素和病理生理特点。本文主要对近年来钙化性主动脉瓣膜病发病机制及治疗进展的研究做一综述。
Aortic stenosis is more common in clinical heart valve disease, the main cause is aortic valve calcification. With the aging of the population, the incidence of calcific aortic valvular disease also continues to increase. Therefore, calcified aortic valve stenosis has been considered as a degenerative disease for more than 20 years. However, in recent years Research progress, a large number of evidence that calcific aortic valve disease is an active pathological process with atherosclerosis with the same risk factors and pathophysiological characteristics. This article mainly reviews the research on the pathogenesis and treatment of calcific aortic valvular disease in recent years.