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湖北省 1999年共收检急性弛缓性麻痹 (AFP)病例粪便标本 2 0 8例 ;脊髓灰质炎 (脊灰 )病毒 (PV)检出率为 6 2 5 % ,较往年显著上升 ;非脊灰肠道病毒 (NPEV)检出率 3 37% ,较往年显著下降 ;肠道病毒 (EV)总检出率显著下降。分析原因认为 ,PV检出率的上升可能与麻痹后突击服疫苗再采集粪便标本 ,以及环境接触染毒等因素有关。以L2 0B细胞置换Hep -2是EV总阳性率显著下降的主要原因 ,也是NPEV检出率下降的重要原因。NPEV检出率下降还可能与多种因素 ,如细胞形态、毒性反应及粪便标本的贮运温度等有关
In Hubei province, a total of 280 stool samples of acute flaccid paralysis (AFP) were collected in 1999. The detection rate of polio (PV) was 62.5%, significantly higher than that in previous years. Non-polio The detection rate of enterovirus (NPEV) was 377%, which was significantly lower than that in previous years. The total detection rate of enterovirus (EV) was significantly decreased. Analysis of the reasons that the PV detection rate may be paralyzed after the paramedic vaccine and re-collection of stool specimens, as well as exposure to environmental exposure and other factors. The substitution of Hep-2 cells with L2 0B cells is the main reason for the significant decrease of the total positive rate of EV and also the important reason for the decrease of the detection rate of NPEV. The decline of NPEV detection rate may also be related to a variety of factors, such as cell morphology, toxicity and stool specimen storage temperature