目的:采用甲氨喋呤联合米非司酮治疗输卵管妊娠40例,对其临床疗效及安全性进行观察,为本病的临床治疗提供依据。方法:甲氨喋呤50mg/m2,1次/日,肌内注射;米非司酮25mg,2次/日,口服,均连续应用5天。定期测血β-HCG直至正常。结果:治愈率92.5%,平均治愈时间为14.52±2.26天,平均住院日数10.23±2.31天。结论:甲氨喋呤联合米非司酮治疗输卵管妊娠临床疗效满意,并发症少,无严重不良反应。 Objective: The use of methotrexate combined with mifepristone treatment of tubal pregnancy in 40 cases, its clinical efficacy and safety were observed for the clinical treatment of this disease provide the basis. Methods: Methotrexate 50mg / m2, 1 times / day, intramuscular injection; mifepristone 25mg, 2 times / day, orally, were continuously applied for 5 days. Blood beta-HCG is measured regularly until normal. Results: The cure rate was 92.5%. The average cure time was 14.52 ± 2.26 days and the average length of stay was 10.23 ± 2.31 days. Conclusion: The combination of methotrexate and mifepristone is effective in treating tubal pregnancy with few complications and no serious adverse reactions.